DNA methylation markers in plasma identified by next-generation sequencing from breast cancer patients

Into the submitted project description is a little bit of the introduction. I want more complementary text. In theory, I want to start with what epigenetics is and how it is regulated. This involves methylation, histone modification, and activity of non-coding RNA such as micro RNA and the effect of non-coding repeating regions in the DNA code.
In addition, I want a little about cancer and breast cancer, its prevalence in the world, methylation markers in breast cancer, and a small section on what cfDNA is 6-8pages

You can also get the answer to this paper securely, anonymously. The paper shall be original with an accompanying originality report.